CONSEQUENCES OF TOXIC STRESS EXPOSURE IN EARLY CHILDHOOD ON NEUROPSYCHOLOGICAL DEVELOPMENT
DOI:
https://doi.org/10.65013/rms.v1i1.9Keywords:
Adverse Childhood Experiences, Developmental Disabilities, Neurodevelopmental Disorders, Psychological StressAbstract
This study aimed to investigate the relationship between Adverse Childhood Experiences (ACE) and the development of developmental disabilities and neurodevelopmental disorders. A quantitative methodology was used, with data analysis collected from interviews and questionnaires applied to a group of children diagnosed with neuropsychiatric disorders. The results indicated that children with a history of ACE showed higher levels of psychological stress and a higher prevalence of developmental disabilities compared to control groups. The study concluded that ACE are significant risk factors for the development of neurodevelopmental disorders, suggesting the need for early interventions to mitigate the impacts of childhood stress.
References
ANDRADE, Célia; AVNCI, Joviana; OLIVEIRA, Raquel. Experiências adversas na infância, características
sociodemográficas e sintomas de depressão em adolescentes de um município do Rio de Janeiro, Brasil. Caderno
de saúde Pública, v. 38, n. 6, p. 1-18, 2022. Disponível em: chromeextension://
efaidnbmnnnibpcajpcglclefindmkaj/https://www.scielo.br/j/csp/a/V7mdBSWV4BqcKK9FPP8NqXS/?f
ormat=pdf. Acesso em: 06 de novembro 2024.
CAMPOS, Dioclécio. The formation of citizens: the pediatrician’s role. Jornal de Pediatria, v. 92, n. 3, p. S23–
S29, 2016. disponível em: https://www.scielo.br/j/jped/a/8P96p9FSYQPxJ3Jg5FzQSJD/?lang=en. Acesso em: 07 de
novembro de 2024;
EICKMANN, Sophie; EMOND, Alan; LIMA, Marília. Evaluation of child development: beyond the neuromotor
aspect. Jornal de Pediatria, v. 92, n. 3, p. S71–S83, 2016. disponível em:
https://www.scielo.br/j/jped/a/8P96p9FSYQPxJ3Jg5FzQSJD/. Acesso em: 06 de outubro de 2024;
Felitti, Vicent; Anda, Roberto; Nordenberg, Dale et al. Relationship of childhood abuse and household dysfunction
to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) Study. American
Journal of Preventive Medicine, v. 14, n. 4, p. 245-258, 1998. Disponível em:
https://pubmed.ncbi.nlm.nih.gov/9635069/. Acesso em: 06 de outubro de 2024;
SHERIDAN, Margaret; MCLAUGHLIN, Katie. Introduction to the special issue on childhood adversity and
neurodevelopment. Developmental Cognitive Neuroscience, v. 54, n. 1, p. 459-471, 2022. Disponível em:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9019832/. Acesso em: Acesso em: 06 de outubro de 2024;
LINHARES, Maria Beatriz. Estresse precoce no desenvolvimento: impactos na saúde e mecanismos de proteção.
Revista Brasileira de Crescimento e Desenvolvimento Humano, v. 26, n. 3, p. 368-374, 2016. Disponível em:
https://www.scielo.br/j/estpsi/a/Sp37RNtbJQKzBPPTKBWJrfj/#. Acesso em: 12 nov. 2024.
LOTT, Abgail; WOODS-JAEGER, Ban. Dialectical Behavior Therapy for Pregnant Women. Clinical Trials, v. 5,
n. 1, p. 1-11, 2019. disponível em: https://clinicaltrials.gov/study/NCT03938350. Acesso em: 06 de novembro de
2024;
LUPIEN, Sonia; MCEWEN, Bruce; GUNNAR, Megan et al. Effects of stress throughout the lifespan on the brain,
behavior, and cognition. Nature Reviews Neuroscience, v. 10, n. 6, p. 434-445, 2009. Disponível em:
https://pubmed.ncbi.nlm.nih.gov/19401723/. Acesso em: 06 de novembro de 2024;
MILLER, Gregory; CHEN, Edith; PARKER, Karen. Psychological stress in childhood and susceptibility to the
chronic diseases of aging: moving toward a model of behavioral and biological mechanisms. Psychological Bulletin,
v. 133, n. 6, p. 985-1006, 2011. Disponível em: https://pubmed.ncbi.nlm.nih.gov/21787044/. Acesso em: 06 de
novembro de 2024;
SHONKOFF, Jack; BOYCE, Wilson; MCEWEN, Bruce. Neuroscience, molecular biology, and the childhood roots
of health disparities: building a new framework for health promotion and disease prevention. JAMA, v. 301, n. 21,
p. 2252-2259, 2012. Disponível em: https://pubmed.ncbi.nlm.nih.gov/19491187/. Acesso em: 12 novembro 2024.
UNICEF. The State of the World's Children 2019: Children, food and nutrition. 2019. Disponível em:
alerta-ounicef#:~:
text=O%20relat%C3%B3rio%20Situa%C3%A7%C3%A3o%20Mundial%20da,est%C3%A1%20desnutr
ida%20ou%20com%20sobrepeso.. Acesso em: 12 de novembro de 2024;
VITRIOL, Verônica; SCIOLLA, Andrês; CANCINO, Alfredo et al. Cuidado Informado En Trauma: Un Modelo
Emergente Para El Abordaje Del Subtipo Depresivo Con Historia De Adversdad Infantil. Revista chilena de neuropsiquiatría,
v. 58, n. 4, p. 348–362, 2020. disponível em:
Acesso em: 06 de outubro de 2024;
WAGNER, Rachel; REID-JONSON, Melissa; DRAKE, Brett et al. Parameterizing Toxic Stress in Early Childhood:
Maternal Depression, Maltreatment, and HPA-Axis Variation in a Pilot Intervention Study. Prevention Science, v.1, n. 7, p. 1-12, 2022. Disponível em: https://link.springer.com/article/10.1007/s11121-022-01366-4. Acesso em: 07
de novembro de 2024;
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Revista Medicina e Saberes
This work is licensed under a Creative Commons Attribution 4.0 International License.
